Diagnosis of Tensilon-Negative Ocular Myasthenia Gravis By Daily Selfie

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Diagnosis of Tensilon-Negative Ocular Myasthenia Gravis By Daily Selfie.

The initial symptoms of myasthenia gravis are usually ptosis and diplopia. The diagnosis is often confirmed by testing for anti-acetylcholine receptor antibodies or by observing the effects of intravenous edrophonium (Tensilon) injection. However, these standard tests may be negative in patients with isolated ocular findings. We present the case of an 83-year-old woman with negative serologic a...

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[Tensilon tonography in the diagnosis of myasthenia gravis].

The concomitant intravenous administration of Tensilon during tonography was performed on a group of 15 myasthenic patients and ten "control" subjects, including patients with oculoparesis of known cause other than myasthenia. The myasthenic group uniformly responded with increases of intraocular pressure. There was no instance of this response in nonmyasthenic subjects when challenged with Ten...

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Ocular Manifestations of Myasthenia Gravis

The cause of the weakness is due to a defect at the level of the neuromuscular junction in which autoimmune antibodies block the receptors responsible for initiating muscular contraction. The neurotransmitter that is subject to this competitive inhibition is acetylcholine (ACh). The muscles commonly affected include those of the neck, limbs and chest cavity with regards to breathing. The muscle...

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Ocular Neuromyotonia and Myasthenia Gravis.

To the Editors: Myasthenia gravis presents with only ocular symptoms (diplopia, ptosis, and extraocular movement limitation) in approximately 20% of patients.1,2 Ocular myasthenia gravis is to be suspected in patients with intermittent diplopia with ophthalmoplegia that does not correspond to a single ocular motor nerve paresis. However, diplopia in only eccentric sustained gaze in myasthenia g...

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Myasthenia gravis: diagnosis.

The clinical history and neurological examination provide the most important data on which the diagnosis of autoimmune myasthenia gravis (MG) is based. MG produces symptomatic weakness that predominates in certain muscle groups and typically fluctuates in response to effort and rest. The diagnosis of MG therefore depends on the recognition of this distinctive pattern of fatigable weakness. Labo...

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ژورنال

عنوان ژورنال: Journal of Neuro-Ophthalmology

سال: 2016

ISSN: 1070-8022

DOI: 10.1097/wno.0000000000000413